Peripheral artery disease (PAD) is a progressive disease occurring as a result of plaque accumulation (atherosclerosis) in the arterial system that carries blood to the extremities (arms and legs) as well as vital organs. The vessels that are most affected by PAD are...
Transcatheter Aortic Valve Implantation (TAVI) for Treatment of Aortic Valve Stenosis: An Evidence-Based Analysis
Transcatheter aortic valve implantation (TAVI) has become an alternative to surgical aortic valve replacement (sAVR) for patients at high risk for surgery. The objective of this analysis is to evaluate the safety, effectiveness, and cost-effectiveness...
Internet-Based Device-Assisted Remote Monitoring of Cardiovascular Implantable Electronic Devices: An Evidence-Based Analysis
The objective of this Medical Advisory Secretariat (MAS) report was to conduct a systematic review of the available published evidence on the safety, effectiveness, and cost-effectiveness of Internet-based device-assisted remote monitoring systems (RMSs) for...
Paclitaxel Drug-Eluting Stents in Peripheral Arterial Disease: A Health Technology Assessment
Peripheral arterial disease is a condition in which atherosclerotic plaques partially or completely block blood flow to the legs. Although percutaneous transluminal angioplasty and metallic stenting have high immediate success rates in treating peripheral arterial...
Left Ventricular Assist Devices for Destination Therapy: A Health Technology Assessment
Left ventricular assist devices help keep blood flowing through the body by assisting a specific chamber in the hearts of patients with severe heart failure. A left ventricular assist device can be implanted as a last resort for patients with severe heart...
Mechanical Thrombectomy in Patients With Acute Ischemic Stroke: A Health Technology Assessment
In Ontario, current treatment for eligible patients who have an acute ischemic stroke is intravenous thrombolysis (IVT). However, there are some limitations and contraindications to IVT, and outcomes may not be favourable for patients with stroke caused by a proximal...
Transcatheter Aortic Valve Implantation for Treatment of Aortic Valve Stenosis: A Health Technology Assessment
The aortic valve is one of four valves in the heart. It allows blood to flow from the left ventricle of the heart into the aorta (the main artery in the body). Aortic valve stenosis occurs if the valve narrows and cannot open all the way, partially blocking the...
Long-Term Continuous Ambulatory ECG Monitors and External Cardiac Loop Recorders for Cardiac Arrhythmia: A Health Technology Assessment
Cardiac arrhythmia is a group of conditions in which the heart is beating too fast, too slow, or erratically. Symptoms of arrhythmia may include chest pain, fainting, dizziness, or a racing or thumping heart. To diagnose an arrhythmia, doctors often use an...
Percutaneous Ventricular Assist Devices: A Health Technology Assessment
The Impella device is a percutaneous ventricular assist device that has a small pump at one end of a thin, flexible tube. It is implanted through an artery in the leg and pumps blood from the left ventricle through the heart valve into a blood vessel called the...
Left Atrial Appendage Closure Device With Delivery System: A Health Technology Assessment
Atrial fibrillation is a common heart disease involving electrical disturbances in the atria (the top two chambers) of the heart, which can reduce the heart’s ability to pump blood efficiently. Nonvalvular atrial fibrillation (atrial fibrillation that does not...
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