Chronic obstructive pulmonary disease (COPD) is a chronic progressive lung disease characterised by non-reversible airflow obstruction. Exacerbations are a key cause of morbidity and mortality and place a considerable burden on health-care systems. While there is...
Invasive home mechanical ventilation, mainly focused on neuromuscular disorders
Invasive home mechanical ventilation is used for patients with chronic respiratory insufficiency. This elaborate and technology-dependent ventilation is carried out via an artificial airway (tracheal cannula) to the trachea. Exact numbers about the incidence of home...
Total hip replacement and surface replacement for the treatment of pain and disability resulting from end-stage arthritis of the hip (review of technology appraisal guidance 2 and 44): systematic review and economic evaluation
Total hip replacement (THR) involves the replacement of a damaged hip joint with an artificial hip prosthesis. Resurfacing arthroplasty (RS) involves replacement of the joint surface of the femoral head with a metal surface covering. The objective of this review was...
Conceptual model for early health technology assessment of current and novel heart valve interventions
The future promises many technological advances in the field of heart valve interventions, like tissue-engineered heart valves (TEHV). Prior to introduction in clinical practice, it is essential to perform early health technology assessment. We aim to develop a...
Mid-wheel drive powered wheelchairs
Mid-wheel drive powered wheelchairs (MWDs) have been extremely popular in the American and Canadian markets for the past few years. The drive wheels of this type of chair are positioned in line with or near the centre of gravity of the chair, while the drive wheels of...
Screening Mammography: A Reassessment
Screening mammography, a technique which is 50 years old, aims to advance the diagnosis of breast cancer in order to offer early treatment, thereby improving the chances of cure. The practice of mammography, in constant evolution, varies widely according to the...
Computed Tomography and Its Carcinogenic Effects in Children and Youth in Québec
Developments in diagnostic radiology have made it possible not only to perform increasingly precise scans and but also to reduce their associated radiation doses. Yet the growing use of these scans in medical practice and the advent of new technologies expose the...
Evaluation of the evidence on the HeartMate II® and HeartWare® ventricular assist devices for the treatment of chronic end-stage heart failure
Heart failure is a complex syndrome that arises when the heart is incapable of pumping enough blood to respond to the metabolic needs of the body. Heart failure is often caused by defective contraction and relaxation of the myocardium, accompanied by elevated cardiac...
Transcatheter aortic valve implantation: Evaluation of the evidence and synthesis of organizational issues
Aortic valvular stenosis, or narrowing of the valve orifice, is a progressive disease that generally affects patients over the age of 65 years in Western countries and is usually caused by degenerative calcification. Aortic stenosis causes increasing resistance...
The Excimer Laser in Ophthalmology
In May 1997, the Conseil d’évaluation des technologies de la santé du Québec (CETS) published a report dealing spe- cifically with excimer laser photorefractive keratectomy (PRK). Since then, the ophthalmological applications of the excimer laser have continued to...
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